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carotid body : ウィキペディア英語版
carotid body

The carotid body (''carotid glomus'' or ''glomus caroticum'') is a small cluster of chemoreceptors and supporting cells located near the fork (bifurcation) of the carotid artery (which runs along both sides of the throat).
The carotid body detects changes in the composition of arterial blood flowing through it, mainly the partial pressure of oxygen, but also of carbon dioxide. Furthermore, it is also sensitive to changes in pH and temperature.
==Structure==
The carotid body is made up of two types of cells, called glomus cells: glomus type I (chief) cells, and glomus type II (sustentacular) cells.
* Glomus type I/chief cells are derived from neural crest, which, in turn are derived from neuroectoderm. They release a variety of neurotransmitters, including acetylcholine, ATP, and dopamine that trigger EPSPs in synapsed neurons leading to the respiratory center.
* Glomus type II/sustentacular cells resemble glia, express the glial marker S100 and act as supporting cells.
The carotid body contains the most vascularized tissue in the human body . The thyroid gland is very vascular, but not quite as much as the carotid body.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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